Our Root 66 South Grand location was the first medical marijuana dispensary to open in the City of St. Louis. South Grand has a flavor all its own. You can travel around the world on South Grand, known locally and regionally as an International District, the neighborhood offers a wide array of activity from unique stores and eclectic shops to a huge array of ethic restaurants.

Root 66 is proud to join the South Grand community and offer patients a wide variety of cannabis products including: cannabis flower, vapes, concentrates, edibles, beverages and more! We pride ourselves on our commitment to the community of South Grand and St. Louis to offer the best experience and widest selection in town.

Root 66 - S Grand (MED)

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Willie Nelson has never made any bones about it. The cannabis culture is a way of life for him. And he has always operated under a simple philosophy: my stash is your stash.
Friends, fans and fellow musicians can attest to that. For decades, as Willie and his band travelled from town to town, pot enthusiasts flocked to his shows, their pockets stuffed with offerings from their home gardens and local communities. They happily shared their bounty. And Willie gladly returned the favor.

Willie's Reserve pays tribute to this tradition of sharing, caring and toking. Now that the cannabis revolution is well underway, it should come as no surprise that Willie is one of its most enthusiastic and committed supporters. His vision guides Willie's Reserve.

Willie's Reserve

SFV OG x Triangle Kush x Hell’s Angels OG

A strong earthy/spicy inhale with citrus notes on the exhale.

The most common effects are happy, hungry, and relaxed.  Helps relieve stress, and social anxiety, and stimulates appetite.

OG Kush [.5g]

OG Kush, also known as "Premium OG Kush,"&nbsp;was first cultivated in Florida&nbsp;in the early ‘90s when a marijuana strain from Northern California was supposedly crossed with <a href="https://www.leafly.com/strains/chemdawg">Chemdawg</a>, <a href="https://www.leafly.com/strains/lemon-thai">Lemon Thai</a> and&nbsp;a <a href="/strains/hindu-kush">Hindu Kush</a> plant from Amsterdam. The result was a <a href="https://www.leafly.com/strains/lists/category/hybrid">hybrid</a> with a unique terpene profile that boasts a complex aroma with notes of fuel, skunk,&nbsp;and spice. OG often refers to “Original Gangster,” or "Ocean Grown" indicating either the strain’s authenticity or intensity. Many people have different names for the acronym, but real&nbsp;OG Kush should smell like lemon-pine-fuel with a high-THC, mixed head and body effect. It's often enjoyed in the back half of the day to ease stress. The genetic backbone of West Coast cannabis varieties, OG Kush arrived in Los Angeles in 1996 when Matt “Bubba” Berger brought it (along with “The Bubba,” which was later used to create the famed <a href="/strains/bubba-kush">Bubba Kush</a>) from Florida to legendary cultivator Josh D. Since then, OG Kush has become a worldwide staple used to create numerous famous strains like <a href="/strains/gsc">GSC</a> and <a href="/strains/headband">Headband</a>. There are many different phenotypes of OG Kush weed, including <a href="/strains/tahoe-og">Tahoe OG</a>, <a href="/strains/sfv-og">SFV OG</a>, and <a href="/strains/ghost-og">Ghost OG</a>.

OG Kush, also known as "Premium OG Kush," was first cultivated in Florida in the early ‘90s when a marijuana strain from Northern California was supposedly crossed with Chemdawg, Lemon Thai and a Hindu Kush plant from Amsterdam. The result was a hybrid with a unique terpene profile that boasts a complex aroma with notes of fuel, skunk, and spice. OG often refers to “Original Gangster,” or "Ocean Grown" indicating either the strain’s authenticity or intensity. Many people have different names for the acronym, but real OG Kush should smell like lemon-pine-fuel with a high-THC, mixed head and body effect. It's often enjoyed in the back half of the day to ease stress.  The genetic backbone of West Coast cannabis varieties, OG Kush arrived in Los Angeles in 1996 when Matt “Bubba” Berger brought it (along with “The Bubba,” which was later used to create the famed Bubba Kush) from Florida to legendary cultivator Josh D. Since then, OG Kush has become a worldwide staple used to create numerous famous strains like GSC and Headband. There are many different phenotypes of OG Kush weed, including Tahoe OG, SFV OG, and Ghost OG.

aroused

creative

energetic

euphoric

focused

giggly

happy

hungry

relaxed

sleepy

talkative

tingly

uplifted

OG Kush

This legendary strain boasts a complex aroma with notes of fuel, skunk, and spice.

OG Kush [.5g]

OG Kush [.5g]

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Root 66 - S Grand (MED)

OG Kush [.5g]

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