I haven't had many side effects from the strains I have tried. I've tried about 30 and Grape Stomper gave me some of the worst side effects I've ever had. I have an anxiety disorder and I use Cannabis to help treat it. This made my anxiety so bad. When I wasn't anxious it was fair. I also had dry mouth and dry eye. The dry eye being the second worse side effect. I just used some moisturizing eye drops and that helped. The dry mouth was very mild and you only need to swish water in your mouth and drink it. I realize not everyone will have the same effects as me with this strain. I will say be careful if you have anxiety problems. It gives a fairly potent head high with enough used. To get high I'd have to smoke 3 bowls from my smallish pipe. 5 if I wanted a stellar experience. Another effect is this will make you somewhat tired. Not a good day strain IMHO.